VaxDome technology delivers a low dose of the virus in combination with a viral propagation inhibitor that allows sequestration of the virus and training of the immune system to prevent infection. Broad, cross-viral immunity is developed.
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Zanamivir (binds to NA)
Influenza
zIFV
Packaged in an easy-to-use intranasal syringe
HA
NA
HA - Hemagglutinin NA - Neuraminidase
Novel Mechanism
zIFV blocks influenza entry and release and sequesters virus within cells
Normal infection process
zIFV infection
zIFV immunization generates tertiary lymphoid structures in lung tissue
zIFV infection only requires 10 infectious units per dose for immunization